Leukotriene modifiers (also known as Leukotriene Receptor Antagonists) are common asthma drugs that have been rarely linked to something called Churg-Strauss syndrome (good trivia fact). The FDA has requested that certain drug manufacturers include a precaution in the drug prescribing information (drug labeling) regarding neuropsychiatric events (behavior, mood changes) that have been reported in some persons taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR).
- Singulair is manufactured by Merck.
- Accolate is manufactured by AstraZeneca
- Zyflo is manufactured by Cornerstone Therapeutics, Inc.