When's the last time you saw a new pain pill? NUCYNTA™ (tapentadol) is a single molecule with a different approach to pain relief. It is the first new molecule in analgesia in over 25 years for the relief of moderate to severe acute pain in adults.
According to a a Phase 3 clinical study published in the June 2009 issue of Current Medical Research and Opinion, tapentadol immediate release (IR) tablets provided patients with equivalent efficacy in pain relief following orthopedic surgery and significant reduction in nausea and/or vomiting compared to oxycodone IR.
NUCYNTA™ combines opioid and nonopioid activity in one centrally acting oral analgesic.
Mu-Opioid Agonist (Ascending Pathways)
- Work primarily on ascending pathways to inhibit transmission of pain impulses through binding to mu-opioid receptors
- Norepinephrine reuptake inhibition works primarily on the descending pathways to enhance the inhibition of pain signaling
There's simply so much we don't understand about pain. It's interesting to see research being done on drugs that have mysterious and unknown mechanisms of actions. We can postulate and theorize, but we can't prove how they work yet.
If you wish to learn more about Nucynta, visit: http://www.nucynta.com
Nucynta is marketed by Ortho-McNeil-Janssen Pharmaceuticals, Inc.