Tuesday, July 20, 2010

How to pronounce vorapaxar

People often struggle with drug name pronunciation. There's a drug that's currently in development called vorapaxar and it's a thrombin receptor antagonist or TRA. Most of us didn't learn about TRAs in medical school.If you're a cardiologist, you've probably heard of vorapaxar or SCH 530348.
Vorapaxar is pronounced vor" a pax' ar.
CHEMICAL NAMES

1. Carbamic acid, [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2- pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, sulfate
2. Ethyl [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)pyridin-2- yl]ethenyl]-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamate sulfate

Here are a few other interesting facts:

MOLECULAR FORMULA C29H33FN2O4 . H2O4S
MOLECULAR WEIGHT 590.7
MANUFACTURER Schering-Plough/Merck
CODE DESIGNATION SCH 530348
CAS REGISTRY NUMBER 705260-08-8

Source: STATEMENT ON A NONPROPRIETARY NAME ADOPTED BY THE USAN COUNCIL (click here to access)

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